Category: Medical / Psychiatry / General

Epilepsy

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Written and edited by world-renowned authorities, this three-volume work is, to quote a reviewer, “the definitive textbook about seizures and epilepsy”. This Second Edition is thoroughly updated and gives you a complete print and multimedia package: the three-volume set plus access to an integrated content Website.

More than 300 chapters cover the spectrum of biology, physiology, and clinical information, from molecular biology to public health concerns in developing countries. Included are detailed discussions of seizure types and epilepsy syndromes; relationships between physiology and clinical events; psychiatric and medical comorbidity; conditions that could be mistaken for epilepsy; and an increasing range of pharmacologic, surgical, and alternative therapies, including vagus nerve stimulation and deep brain stimulation. This edition describes many new antiepileptic drugs, major advances in surgical treatment, and state-of-the-art neuroimaging, EEG, and other technologies for diagnosis and seizure prediction.

A companion Website offers instant access to the complete, fully searchable text, plus an image bank of additional figures, video footage, and annual updates to selected chapters.

The Boundaries of Consciousness: Neurobiology and Neuropathology

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Consciousness is one of the most significant scientific problems today. Renewed interest in the nature of consciousness – a phenomenon long considered not to be scientifically explorable, as well as increasingly widespread availability of multimodal functional brain imaging techniques (EEG, ERP, MEG, fMRI and PET), now offer the possibility of detailed, integrated exploration of the neural, behavioral, and computational correlates of consciousness. The present volume aims to confront the latest theoretical insights in the scientific study of human consciousness with the most recent behavioral, neuroimaging, electrophysiological, pharmacological and neuropathological data on brain function in altered states of consciousness such as: brain death, coma, vegetative state, minimally conscious state, locked-in syndrome, dementia, epilepsy, schizophrenia, hysteria, general anesthesia, sleep, hypnosis, and hallucinations. The interest of this is threefold. First, patients with altered states of consciousness continue to represent a major clinical problem in terms of clinical assessment of consciousness and daily management. Second, the exploration of brain function in altered states of consciousness represents a unique lesional approach to the scientific study of consciousness and adds to the worldwide effort to identify the “neural correlate of consciousness”. Third, new scientific insights in this field have major ethical and social implications regarding our care for these patients.

Escourolle and Poirier’s Manual of Basic Neuropathology

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Now in its 5th edition, Escourolle and Poirier Manual of Basic Neuropathology continues the tradition of being one of the most respected texts in neuropathology by providing an introduction to the various diseases of the nervous system and their underlying pathology. This thorough, yet concise manual covers the full spectrum of the various categories of neurologic disease, including neoplasia, trauma, vascular disease, and infection, with separate chapters on prion diseases, multiple sclerosis, degenerative disorders, acquired metabolic diseases, hereditary metabolic diseases, congenital malformations, perinatal diseases, skeletal muscle, peripheral nerve, and the pituitary gland. To accurately guide the clinician, the most current techniques in neuropathology are covered in their own chapter at the end of the book. Richly illustrated throughout, with over 700 images of various neuropathogical diagnoses such as tumor, stroke, infection, degeneration, and malformation among others, this new edition of the classic monograph is an easy-to-use manual for any student, researcher, or practitioner seeking basic information on neuropathology. Used for decades in all fields related to the nervous system-including neurology, neurosurgery, psychiatry, neuroradiology, neuroendocrinology, neuropathology, pathology, and neuroscience- Escourolle and Poirier Manual of Basic Neuropathology is regarded at the ‘bible’ of neuropathology. This new version has been completely rewritten and expanded to include important updates in genetics and molecular biology, reflective of the important neuropathological discoveries in those fields over the past decade.This book is a practical diagnostic tool and necessary reading for anyone encountering pathological conditions of the nervous system.

The Neuropathology of Dementia

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Completely rewritten and updated, this new edition is almost twice the size of its predecessor. Illustrated in colour throughout, and with contributions from the world’s leading authorities, it is the definitive reference on the neuropathology of dementia. It gives practical guidance to pathologists, describes the contribution of neuroimaging to diagnosis, and surveys the clinical features of dementia. New material includes:

  • Three entirely new chapters on neuroimaging, molecular diagnostics, and transgenic models.
  • Two chapters on tauopathies under new authorship.
  • A chapter under new authorship on synucleinopathies, which includes multiple system atrophy.
  • Neurophysiology and Neuropsychology of Motor Development

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    The central focus of this book is the development of skilled motor actions by children; commonplace but vital actions such as maintaining posture, walking, reaching and grasping, and manipulating objects and tools. It represents a state-of-the art report on motor development linking neurophysiological and neuropsychological approaches. Using examples from both normal and pathological development, contributions study pre and postnatal brain development and its relationship to movement, the importance of fetal movements, postural control in children, the neurobiology of locomotor development, neural mechanisms of grasping and typical patterns of behavioural change. New theoretical developments including adaptive model theory, dynamic systems theory, and the relationship between variability and stability in skill development are also critically reviewed.

    Clinical Neuroanatomy

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    A major focus of clinical neuropsychology and cognitive-behavioral neurology is the assessment and management of cognitive and behavioral changes that result from brain injury or disease. In most instances, the task of the neuropsychologist can be divided into one of two general categories. Perhaps the most common is where patients are known to be suffering from identi?ed neurological insults, such as completed strokes, neoplasms, major head traumas or other disease processes, and the clinician is asked to assess the impact of the resulting brain damage on behavior. The second involves differential diagnosis in cases of questionable insults to the central nervous system. Examples of the latter might be milder forms of head trauma, anoxia and dementia or suspected vascular compromise. In either instance, understanding the underlying pathology and its consequences depends in large part on an analysis of cognitive and behavioral changes, as well as obtaining a good personal and medical history. The clinical investigation will typically include assessing problems or changes in personality, social and environmental adaptations, affect, cognition, perception, as well as sensorimotor skills. Regardless of whether one approaches these questions having prior independent con?rmation of the pathology versus only a suspicion of pathology, a fairly comprehensive knowledge of functional neuroanatomy is considered critical to this process. Unfortunately as neuropsychologists we too frequently adopt a corticocentric view of neurological de?cits. We recognize changes in personality, memory, or problem solving capacity as suggestive of possible cerebral compromise.

    Child Neurology

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    Revised to incorporate the latest advances in the neurosciences and clinical neurology, the Seventh Edition of this classic text provides practical, cost-effective problem-solving approaches to all diseases affecting the developing nervous system. In clinically relevant terms, the book explains how recent developments in molecular biology, genetics, neurochemistry, neurophysiology, neuropathology, and neuroimaging impact on diagnosis and treatment.

    Chapters focus on specific disorders or groups of disorders and emphasize differential diagnosis, disease course, treatment, and prognosis. This edition has a new chapter on mitochondrial cytopathies.

    Merritt’s Neurology

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    The thoroughly updated Twelfth Edition of this classic retains the organization, practicality, and readability that makes Merritt’s Neurology one of the most popular texts among neurologists, primary care physicians, and residents reviewing for psychiatry or neurology boards. In 183 short chapters, the book provides the essentials clinicians need on symptoms/signs, diagnostic tests, and neurologic disorders of all etiologies.

    For this edition, Timothy A. Pedley, MD, Chair of the Department of Neurology at Columbia University, joins Dr. Rowland as co-editor. Coverage includes separate chapters on autism, autosomal recessive ataxias, and autosomal dominant ataxias, and new chapters on endovascular neuroradiology, parkinsonian syndromes, Lewy body dementias, frontotemporal dementia, vanishing white matter, vasculitis, normal pressure hydrocephalus, neuromyelitis optica, Kennedy disease, spinal muscular atrophy, complex regional pain syndrome, disorders of DNA translation, the immune restoration inflammatory syndrome (IRIS), and Hashimoto encephalopathy. Most chapters have been updated to reflect advances in molecular genetics.

    A companion Website will offer the fully searchable text and an image bank.